Neurologger 2A

Neurologgers of the second generation were designed to record a large set of biological variables  (up to 4 analog channels) in their large integrated memory (1 GB or, 2 GB), having size and weight suitable for attachment to a head of a mouse or a back of a zebra finch (small song bird weighing 14-17 g). The minimal weight of recording module  including two ZA5 35 mAh batteries is 1.3 g, the size is 22×15×5 mm.


Infrared (IR) receiver
for synchronization

3-D accelerometer

Connector for
electrophysiological
signals

4 neurophysiological channels with sampling rate up to 20 kHz
for EEG, ECG, EOG, EMG, LFPs and neuronal activity.
3-D accelerometer
Infrared (IR) synchronization with external equipment.
The recorder weight in the most complete configuration is 1.71 g
+ ~1 g typical battery weight makes total weight 2.71 g.
The battery holder can add 0.63 g.

 

Neurologger 2A other variants

Neurologger with 3D accelerometer, 3D gyroscope and 3D magnetometer for
3D animal head orientation tracking. All these sensors have 16-bit resolution.
An additional 24-bit resolution pressure sensor helps to determing altitude, for instance,
in a freely-flying bird.
24-bit thermometer is capable to catch even tiny fluctuations of ambient temperature.

Built-in IR receiver is used not only for synchronization with external erquipment,
but also can be used for remote ON/OFF of Neurologger and optiogenetic stimulation control.

Only
3-D accelerometer,
256 MB memory,
weight 1.28 g
The lightest version:
electrodes are soldered
directly to the board,
clip connector for data
downloading, 1 GB,
weight 0.95 g
The same as before
but with the connector
for the electrodes,
weight 1.05 g
Micro board with
3-D accelerometer
is added, weight of
recording combination
1.61 g

Water-proof ECG recorder for marine birds
IR receiver is replaced by magnetic sensor.
Putting permanent magnet in the vicinity
of the sensor creates a label in the logger record.
Memory 1 GB, rechargeable battery 3.7V, 240 mAh.
The battery is sufficient for 4 days.
Total weight of encapsulated logger 20 g.

 

Neurologger 2A can record:

  • EEG (electroencephalogram)
  • LFPs (local field potentials)
  • Neuronal activity
  • EMG (electromyogram)
  • ECG (electrocardiogram)
  • Animal vocalizations below 10 kHz
  • 3-D acceleration
  • Event labels for precise synchronization with external equipment

Neurologger can be implanted to record brain activity, for instance, in large ruminants, or it can be placed in a rigid protective waterproof casing to record in  marine environments. Just ask!

Neurologger 2A has been used in the recent publications:

Perinot et al., 2024
Conners et al., 2024
Ba et al., 2024
van Hasselt et al., 2024
Chen et al., 2024
- In Nature Communications!
Zaid et al., 2024
Sotelo et al., 2023
van Hasselt et al., 2023
Tossell et al., 2023 - In Nature Neuroscience!
Yu et al., 2022 - In Science the 2nd time!
Miracca et al., 2022
Zaid et al., 2022
Johnsson et al., 2022
Harding et al., 2021
Johnsson et al., 2021
van Hasselt et al., 2021a
van Hasselt et al., 2021
van Hasselt et al., 2020b
Conelly et al., 2020
Aulsebrook et al., 2020
Padovani et al., 2020
Yu et al., 2020
van Hasselt et al., 2020a
van Hasselt et al., 2020
Ma et al., 2019
Gent et al., 2019
Allocca et al., 2019
Yu et al., 2019
Delotto et al., 2019
Yu et al., 2019 - In Nature Neuroscience!
Tisdale et al., 2018
Müller et al., 2018
Harding et al., 2018
Gent et al., 2018
Gelegen et al., 2018
Nair et al., 2018
Scriba et al., 2017b
Müller et al., 2017

Tisdale et al., 2017
Scriba et al., 2017a
Franklin et al., 2017 - In Nature Neuroscience!
Nair et al., 2016
Uygun et al., 2016
Rattenborg et al., 2016
- In Nature Communications!
Zhang et al., 2016
Yu et al., 2015 - In Neuron!
Shine et al., 2015
Zhang et al., 2015 - In Nature Neuroscience!
Yu et al., 2014
Anisimov et al., 2014- In Nature Methods!
Backer et al., 2014
Scriba et al., 2014
Voirin et al., 2014
Amendola et al., 2014
Gelegen et al., 2014
Zhan et al. 2014 - In Nature Neuroscience!
Duriez et al. 2014
Scriba et al., 2013b
Scheffzük et al., 2013
Scriba et al., 2013a
Zecharia et al., 2012
Lesku et al., 2012 - Finally in Science!
Brankack et al., 2012
Scheffzük et al., 2011


Previous modification Neurologger 2
has been used in the following studies:

Brankack et al., 2010
Pang et al., 2009

Vyssotski et al., 2009
Rattenborg et al., 2008

 

Attention current Neurologger 2 users!
The latest version of Downloader utility is
Ver. 2.03 (21.10.2023).
Now utility converts data to
European Data Format (EDF).
Please update if you have an earlier version.

NEW: Neurologger 2A/2B received
LED status indicator!
Previos releases can be updated.
Please contact!

Neurologger 2A with remote ON/OFF
and configuring by the magnet for
implantation in marine animals.
LED flash confirms operation success.


Neurologger 2/2A/2B


Neurologger 2 on a mouse


An example of Neurologger 2 neuronal record
(tetrode in the nidopallium of a homing pigeon)

 

 
Neurologger 2 on the head of a homing pigeon   Neurologger 2 on the head of a homing pigeon.
GPS logger is attached at the back

Technical data of the Neurologger 2A/2B

Number of channels:

4 with 2 ref. inputs
(ch1 and ch2 to ref1; ch3 and ch4 to ref2)

ADC resolution:

10 bit

Input range is factory-adjustable. Typical ranges are:

+/- 500 μV for EEG
+/- 1 mV for neuronal activity
+/- 3 mV for LFPs
+/- 6 mV for ECG

Neurologger mechanical dimensions (without batteries):

22x15x3 mm 3

Total mechanical dimensions (Neurologger, batteries):

22x15x5 mm 3

Weight of 1GB Neurologger board:

0.945 g

Weight of two 80mAh Renata ZA10 batteries:

0.635 g

Weight of head connector:

0.255 g

Weight of protective cover:

0.170 g

Weight of battery connecting wires:

0.050 g

Total weight:

2.055 g

Battery life time:

EEG logger, 4 channels,
100, 200 or 400 sps

1 day 9 h

Single unit logger, 4 ch x 9.6 ksps

23 h

1 GB memory data filling time:

4 channels, 100 sps

20 days 17 h

4 channels, 200 sps

10 days 8 h

4 channels, 400 sps

5 days 4 h

4 channels, 1600 sps

1 day 7 h

4 channels + 3D accelerometer, 100 sps

13 days 19 h

4 channels + 3D accelerometer, 200 sps

6 days 21 h

4 channels + 3D accelerometer, 400 sps

3 days 10 h

4 channels + 3D accelerometer, 1600 sps

20 h 42 min

4 channels, 9.6 ksps (with or w/o 3D accelerometer)

5 h 10 min

4 channels, 19.2 ksps (with or w/o 3D accelerometer)

2 h 35 min

4 channels, 33.3 ksps (with or w/o 3D accelerometer)

1 h 29 min

1 channels, 200 ksps (with or w/o 3D accelerometer)

59 min 39 s

1 GB data downloading time:

27 min 2 s

Interface:

3 SPI, 8Mbps, converted to USB via custom adapter, power supply, one CMOS digital input for events recording (shared with SPI pin)

Data format:

Custom

 

Neurologger is a registered trademark.
Protected by U.S. patents #8,160,688; #9,492,085; #11,134,864. Other patents pending.